It is a disease caused by the inability of the adrenal glands to release hormones (due to adrenal cortex damage). Disruption to the immune system is responsible in the majority of cases [3]. More specifically, an autoimmune attack (i.e. an attack carried out by one's own immune system) on the adrenal cortex is a likely cause [2].
Symptoms
Symptoms include weakness, wasting, hypotension (low blood pressure) and having a darker skin complexion [1]. Furthermore, feeling dehydrated and the loss of weight are also symptoms [3].
Treatment
Treatment involves relevant HRT (hormone replacement therapy) in order to replace the lost hormones [1].References
[1] Geddes and Grosset (1996) 'Medical Terms', New Lanark, Geddes & Grosset.
[2] Martin, E. (2015) 'Addison’s disease', Concise Medical Dictionary, [Online], Oxford University Press. Available at: http://www.oxfordreference.com/view/10.1093/acref/9780199687817.001.0001/acref-9780199687817-e-12118 (Accessed on 19th December 2016).
[3] NHS (2015) 'Addison’s disease', NHS Choices [Online]. Available at: http://www.nhs.uk/conditions/Addisons-disease/Pages/Introduction.aspx (Accessed on 19th December 2016).